of April 16 , 2017 . This information is current as Induced by IL - 16 Preferential Migration of T Regulatory Cells Cruikshank

of February 23 , 2013 . This information is current as Induced by IL - 16 Preferential Migration of T Regulatory Cells

This information is current as Induced by IL - 16 Preferential Migration of T Regulatory Cells

Induced by IL-16 Preferential Migration of T Regulatory Cells

Cutting edge: IL-16/CD4 preferentially induces Th1 cell migration: requirement of CCR5.

IL-16 binds to CD4 and induces a migratory response in CD4(+) T cells. Although it has been assumed that CD4 is the sole receptor and that IL-16 induces a comparable migratory response in all CD4(+) T cells, this has not been investigated. In this study, we determined that IL-16 preferentially induces a migratory response in Th1 cells. Because chemokine receptor CCR5 is expressed predominantly ...

A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis.

In contrast to mammals, the medicinal leech Hirudo medicinalis can completely repair its central nervous system (CNS) after injury. This invertebrate model offers unique opportunities to study the molecular and cellular basis of the CNS repair processes. When the leech CNS is injured, microglial cells migrate and accumulate at the site of lesion, a phenomenon known to be essential for the usual...